pan pdk1 site 190 pkcγ thr514 p antibody (Cell Signaling Technology Inc)
93
Structured Review
Cell Signaling Technology Inc
pan pdk1 site 190 pkcγ thr514 p antibody
Pan Pdk1 Site 190 Pkcγ Thr514 P Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 128 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pan+pdk1+site+antibody/Phospho-PKC+(pan)+(gamma+Thr514)+Antibody/10__1128_slash_mcb__00230___16-72-18-52
Average 93 stars, based on 128 article reviews
Pan Pdk1 Site 190 Pkcγ Thr514 P Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 128 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pan+pdk1+site+antibody/Phospho-PKC+(pan)+(gamma+Thr514)+Antibody/10__1128_slash_mcb__00230___16-72-18-52
Average 93 stars, based on 128 article reviews
pan pdk1 site 190 pkcγ thr514 p antibody - by Bioz Stars,
2026-10
93/100 stars
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Western Blot:Article Title: Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P3-dependent mechanisms leading to resistance to PDK1 inhibitors. Article Snippet: Mutations leading to inappropriate activation of Akt isoforms contribute to proliferation and survival of a significant proportion of human cancers.. Akt is activated by phosphorylation of its T-loop residue (Thr) by PDK1 (3-phosphoinositide-dependent kinase-1) and its C-terminal hydrophobic motif (Ser) by mTORC2 [mTOR (mammalian target of rapamycin) complex 2].. Potent PDK1 inhibitors such as GSK2334470 have recently been elaborated as potential anti-cancer agents. Article Title: Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors Article Snippet: Anti-(phospho-Akt Ser 473 ) (#9271), anti-(phospho-Akt Thr 308 ) (#4056), anti-(phospho-S6 ribosomal protein Ser 235 /Ser 236 ) (#4856), anti-(total S6 ribosomal protein) (#2217), anti-PTEN (#9559) and anti-phospho-NDRG1 Thr 346 (#5482) antibodies were purchased from Cell Signaling Technology. .. For immunoblotting of the phosphorylated T-loop of SGK1, we employed the Article Title: Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors Article Snippet: Anti-(phospho-Akt Ser473) (#9271), anti-(phospho-Akt Thr308) (#4056), anti-(phospho-S6 ribosomal protein Ser235/ Ser236) (#4856), anti-(total S6 ribosomal protein) (#2217), anti-PTEN (#9559) and anti-phospho-NDRG1 Thr346 (#5482) antibodies were purchased from Cell Signaling Technology. .. For immunoblotting of the phosphorylated T-loop of SGK1, we employed the Phospho-proteomics:Article Title: Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors Article Snippet: *MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., and †Oncology iMED, AstraZeneca, Alderley Park, Cheshire SK10 4TG, U.K. .. Figure S1 Characterization of Transfection:Article Title: Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors Article Snippet: *MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., and †Oncology iMED, AstraZeneca, Alderley Park, Cheshire SK10 4TG, U.K. .. Figure S1 Characterization of |